Lower serum interleukin‐22 and interleukin‐35 levels are associated with disease status in neuromyelitis optica spectrum disorders
نویسندگان
چکیده
منابع مشابه
Treatment of neuromyelitis optica/neuromyelitis optica spectrum disorders with methotrexate
BACKGROUND To review our experience using methotrexate as a single long-term immunosuppressant (IS) therapy in neuromyelitis optica/neuromyelitis optica spectrum disorders (NMO/NMOSD). METHODS We performed a retrospective chart review of all patients with a diagnosis of NMO/NMOSD, supported by a positive NMO-IgG testing, who were treated with methotrexate. A paired sample 2 tailed t test was ...
متن کاملNeuromyelitis Optica Spectrum Disorders: Diagnosis and Treatment
The last decade has witnessed rapid developments in the clinical understanding and scienti fi c foundati on of neuromyeliti s opti ca (NMO). The landmark events were the late 19th century report by Devic and Gault describing the associati on of severe acute transverse myeliti s and opti c neuriti s and the late 20th century discovery that the syndrome was associated with a specifi c autoanti bo...
متن کاملNeuromyelitis optica spectrum disorders without and with autoimmune diseases
BACKGROUND Neuromyelitis optica spectrum disorder (NMOSD) can coexist with non-organ-specific or organ-specific autoimmune diseases. The aim of this study was to investigate and compare the features between NMOSD without and with autoimmune diseases, and NMOSD with non-organ-specific and organ-specific autoimmune diseases. METHODS One hundred and fifty five NMOSD patients without autoimmune d...
متن کاملTumefactive Brain Lesions in Patients with Neuromyelitis Optica Spectrum Disorder
Background: Neuromyelitis Optica Spectrum Disorder (NMOSD) is an autoimmune neurological disorder that is characterized by optic neuritis and longitudinally-extended transverse myelitis lesions in spinal segments. Magnetic Resonance Imaging (MRI) findings are part of the diagnostic process in NMOSD patients, and abnormal lesion patterns may cause deviation from a correct diagnosis. Clinical P...
متن کاملNeuromyelitis optica spectrum disorders in children and adolescents.
Neuromyelitis optica (NMO) is a severe autoimmune disease of the CNS characterized by recurrent inflammatory events primarily involving the optic nerves and spinal cord. NMO is infrequent in children, but early recognition is important to start adequate treatment. In this article, we review the evolving diagnostic criteria of NMO and provide an update on the clinical and neuroimaging spectrum o...
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ژورنال
عنوان ژورنال: CNS Neuroscience & Therapeutics
سال: 2019
ISSN: 1755-5930,1755-5949
DOI: 10.1111/cns.13198